Publications

A full list of publications can be found on Pubmed

Check out our Google Scholar information

2025

Joo, Y.K., Parrado, C.R., Li, W., Yang, R., Black, E., Bleichert, F., Liu, Y., and Kabeche, L. (2025). The mitotic ATR-Chk1 pathway promotes CDK1 activity for faithful chromosome segregation. Cell Reports 44. 10.1016/j.celrep.2025.116019.

2024

Black EM, Ramírez Parrado CA, Trier I, Li W, Joo YK, Pichurin J, Liu Y, Kabeche L. Chk2 sustains PLK1 activity in mitosis to ensure proper chromosome segregation. bioRxiv [Preprint]. 2024 Mar 12:2024.03.08.584115. doi: 10.1101/2024.03.08.584115. PMID: 38559033; PMCID: PMC10979866.

2023

Joo YK, Black EM, Trier I, Haakma W, Zou L, Kabeche L. ATR promotes clearance of damaged DNA and damaged cells by rupturing micronuclei. Mol Cell. 2023 Oct 19;83(20):3642-3658.e4. doi: 10.1016/j.molcel.2023.09.003. Epub 2023 Oct 2. PMID: 37788673; PMCID: PMC10599252.

Trier I, Black EM, Joo YK, Kabeche L. ATR protects centromere identity by promoting DAXX association with PML nuclear bodies. Cell Rep. 2023 May 30;42(5):112495. doi: 10.1016/j.celrep.2023.112495. Epub 2023 May 9. PMID: 37163376.

2022

Black EM, Joo YK, Kabeche L. Keeping RelApse in Chk: molecular mechanisms of Chk1 inhibitor resistance in lymphoma. Biochem J 2022, 479: 2345-2349. PMID: 36416754, DOI: 10.1042/BCJ20220461.

2018

Lilian Kabeche, Hai Dang Nguyen, Remi Buisson, Lee Zou. A mitosis-specific and R loop–driven ATR pathway promotes faithful chromosome segregation (2018) Science. Jan 5;359(6371).

2017

Sierra N Cullati, Lilian Kabeche, Arminja N Kettenbach, Scott A Gerber. A bifurcated signaling cascade of NIMA-related kinases controls distinct kinesins in anaphase (2017) Journal of Cell Biology. Aug 7;216(8).

Samuel F Bakhoum, Lilian Kabeche, Duane A Compton, Simon N Powell, Holger Bastians. Mitotic DNA damage response: at the crossroads of structural and numerical cancer chromosome instabilities (2017) Trends in Cancer. Mar 1;3(3).

2016

Valentine Comaills, Lilian Kabeche, Robert Morris, Rémi Buisson, Min Yu, Marissa Wells Madden, Joseph A LiCausi, Myriam Boukhali, Ken Tajima, Shiwei Pan, Nicola Aceto, Srinjoy Sil, Yu Zheng, Tilak Sundaresan, Toshifumi Yae, Nicole Vincent Jordan, David T Miyamoto, David T Ting, Sridhar Ramaswamy, Wilhelm Haas, Lee Zou, Daniel A Haber, Shyamala Maheswaran. Genomic instability is induced by persistent proliferation of cells undergoing epithelial-to-mesenchymal transition (2016) Cell Reports. Dec 6;17(10).

2015

Amanda Meppelink, Lilian Kabeche, Martijn JM Vromans, Duane A Compton, Susanne MA Lens. Shugoshin-1 balances Aurora B kinase activity via PP2A to promote chromosome bi-orientation (2015) Cell Reports. Apr 28;11(4).

Samuel F Bakhoum, Lilian Kabeche, Matthew D Wood, Christopher D Laucius, Dian Qu, Ashley M Laughney, Gloria E Reynolds, Raymond J Louie, Joanna Phillips, Denise A Chan, Bassem I Zaki, John P Murnane, Claudia Petritsch, Duane A Compton. Numerical chromosomal instability mediates susceptibility to radiation treatment (2015) Nature Communications. Jan 21;6(1).

Kristina M Godek, Lilian Kabeche, Duane A Compton. Regulation of kinetochore–microtubule attachments through homeostatic control during mitosis (2015) Nature Reviews Molecular Cell Biology. Jan;16(1).

2014

Samuel F Bakhoum, Lilian Kabeche, John P Murnane, Bassem I Zaki, Duane A Compton. DNA-damage response during mitosis induces whole-chromosome missegregation (2014) Cancer Discovery. Nov 1;4(11).

Marianna Kleyman, Lilian Kabeche, Duane A Compton. STAG2 promotes error correction in mitosis by regulating kinetochore–microtubule attachments (2014) Journal of Cell Science. Oct 1;127(19).

2013

Lilian Kabeche, Duane A Compton. Cyclin A regulates kinetochore microtubules to promote faithful chromosome segregation (2013) Nature. Oct;502(7469).

2012

Ana RR Maia, Zaira Garcia, Lilian Kabeche, Marin Barisic, Stefano Maffini, Sandra Macedo-Ribeiro, Iain M Cheeseman, Duane A Compton, Irina Kaverina, Helder Maiato. Cdk1 and Plk1 mediate a CLASP2 phosopho-switch that stabilizes kinetochore–microtubule attachments (2012) Journal of Cell Biology. Oct 15;199(2).

Lilian Kabeche, Duane A Compton. Checkpoint-independent stabilization of kinetochore-microtubule attachments by Mad2 in human cells (2012) Current Biology. Apr 10;22(7).